Mycobacterium lepraemurium
| Mycobacterium lepraemurium | |
|---|---|
| Scientific classification | |
| Kingdom: | Bacteria |
| Phylum: | Actinobacteria |
| Order: | Actinomycetales |
| Suborder: | Corynebacterineae |
| Family: | Mycobacteriaceae |
| Genus: | Mycobacterium |
| Species: | M. lepraemurium |
| Binomial name | |
| Mycobacterium lepraemurium Marchoux and Sorel 1912[1] | |
Mycobacterium lepraemurium is a causative agent of feline leprosy.[2] It causes granulomatous lesions, characteristic of the Mycobacterium genus.
Description
Gram-positive, nonmotile and strongly acid-fast rods (3-5 µm long). Slightly rounded ends.
Colony characteristics
- Rough nonchromogenic colonies.
Physiology
- Growth on inspissated 1% egg yolk medium at 30 °C - 37 °C within 4–5 weeks (using large inocula, confined to a concentrated area of the medium, egg white is inhibitory).
Pathogenesis
- Cause of endemic disease of rats in various parts of the world, as well as feline leprosy.
- feline leprosy is transmitted by bites from rats and other cats.
- Disease occurs mainly in the skin and lymph nodes, causing induration, alopecia and eventual ulceration.
- Nodular lesions, involving subcutaneous tissues, may be solitary or multiple and usually confined to the head region or the limbs. Nodules are fleshy and freely movable.
- Surgical excision of the lesions is the preferred treatment.
- Only the densely and uniformly stained forms appear to be infectious for animals, in contrast to the degenerate unevenly stained forms.
- Biosafety level 2
Type strain
None specified due to difficulties in cultivation.
References
- ↑ Marchoux,F., E. Sorel. 1912. Recherches sur la lèpre. Annales de l'Institut Pasteur (Paris), 26, 675-700.
- ↑ Hughes MS, James G, Taylor MJ, et al. (August 2004). "PCR studies of feline leprosy cases". J. Feline Med. Surg. 6 (4): 235–43. doi:10.1016/j.jfms.2003.09.003. PMID 15265479.
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