Discodermia dissoluta

Discodermia dissoluta
Scientific classification
Kingdom: Animalia
Phylum: Porifera
Class: Demospongiae
Order: Tetractinellida
Family: Theonellidae
Genus: Discodermia
Species: D. dissoluta
Binomial name
Discodermia dissoluta
(Schmidt, 1880)[1]

Discodermia dissoluta is a deep-water marine sponge found in the Eastern, Southern, and Southwestern Caribbean, and in the Greater Antilles.[1][2]

D. dissoluta is of interest from a drug discovery perspective because it produces (+)-discodermolide, a polyketide natural product with immunosuppressive and antiproliferative properties.[3]

References

  1. 1 2 "Discodermia dissoluta Schmidt, 1880". WoRMS. 2015. Retrieved 6 Feb 2016.
  2. ↑ Brück WM, Sennett SH, Pomponi SA, Willenz P, McCarthy PJ (2008). "Identification of the bacterial symbiont Entotheonella sp. in the mesohyl of the marine sponge Discodermia sp.". The ISME Journal. 2: 335–339. doi:10.1038/ismej.2007.91.
  3. ↑ Singh R, Sharma M, Joshi P, Rawat DS (2008). "Clinical status of anti-cancer agents derived from marine sources". Anticancer Agents in Medicinal Chemistry. 8 (6): 603–617. doi:10.2174/187152008785133074. PMID 18690825.


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